Anna Zatonskih has created a solid lead for herself at 4 1/2 points, and has beaten her primary opponent going into the tournament, Irina Krush. Camilla Baginskaite and Alisa Melekhina are both at 3 1/2 points - pulling ahead of Irina Krush by an entire point.
Zatonskih will be playing Melekhina this round, and given Melekhina's surprising performance so far it's expected to be a very interesting match.
Alisa Melehkina gave an interview yesterday that's available
HERE; here's a little sample of the interview by Mike Klein, FunMaster:
Alisa Melekhina, 18, of Philadelphia, is the youngest played in the field as she competes in her second U.S. Women's Championship, an invitation-only event held this year at the Chess Club and Scholastic Center of Saint Louis. During the only free day from competition, Melekhina, a sophomore at Drexel University, has to spend the morning studying for a test in cognitive psychology. In 2007, she played in her first championship, and she was again the youngest.

After five rounds of play this year, Melekhina is tied for second place (with a woman more than twice her age) with 3.5 points out of five. She trails only the defending champion, Anna Zatonskih, of Long Island, N.Y., who is 13 years her senior, a virtual extra lifetime in the world of chess experience.
"I'm not that young anymore," she insisted.